Default Mode Network Oscillatory Coupling Is Increased Following Concussion

CBF-CMRO2 Coupling in the Default Mode Network

Introduction: The Default Mode Network (DMN) has recently attracted attention in the neuroscience community [1]. The DMN is characterized by task independent deactivation a decrease in regional brain activity as measured by cerebral blood flow (CBF) [2,11] or the blood oxygen level dependent (BOLD) signal [3,4], during an arbitrary cognitive task relative to baseline. It is still unclear whethe...

Brain's Default Mode Network

Reduced default mode network connectivity following combat trauma.

Recent studies show decreased functional connectivity in the default mode network (DMN) in PTSD; however, few have directly examined combat trauma specifically. There is limited understanding of how combat itself may affect the DMN. Some literature suggests that trauma exposure, rather than PTSD, can disrupt the DMN. To further elucidate the effect of trauma and PTSD on the DMN, we investigated...

Precuneus is a functional core of the default-mode network.

Efforts to understand the functional architecture of the brain have consistently identified multiple overlapping large-scale neural networks that are observable across multiple states. Despite the ubiquity of these networks, it remains unclear how regions within these large-scale neural networks interact to orchestrate behavior. Here, we collected functional magnetic resonance imaging data from...

Default Mode Network Connectivity in Stroke Patients

The pathophysiology of episodic memory dysfunction after infarction is not completely understood. It has been suggested that infarctions located anywhere in the brain can induce widespread effects causing disruption of functional networks of the cortical regions. The default mode network, which includes the medial temporal lobe, is a functional network that is associated with episodic memory pr...